Hyatt Regency Bethesda
7:00 - 8:00 AM | Light Breakfast |
8:00 - 8:15 AM | Welcome and Introductions Stephen I. Katz, M.D., Ph.D., Director, NIAMS Richard Hodes, M.D., Director, NIA Julie Wolf-Rodda, MA, Director of Partnership Development — Foundation for NIH Gayle Lester, Ph.D., Project Officer for the OAI, NIAMS |
Session I — Where is the OAI Now?
Moderators: | Belinda Seto, Ph.D., Deputy Director, NIBIB Norman Braveman, Ph.D., Assistant to the Director, NIDCR |
8:15 - 8:45 AM | OAI — Where Did We Start and Where Are We Now? Michael Nevitt, Ph.D., University of California San Francisco, PI OAI Coordinating Center |
8:45 - 9:15 AM | How Can Investigators Use the OAI Resource? Charles McCulloch, Ph.D., University of California San Francisco, Biostatistics |
9:15 - 9:45 AM | Role of Biomarker Initiatives in FDA Critical Path Program Janet Woodcock, M.D., Director, Center for Drug Evaluation and Research, FDA |
9:45 - 10:00 AM | Pharmaceutical Industry Perspective on Biomarker Initiatives Monica Luchi, M.D., Novartis |
10:00 - 10:15 AM Break
Session II — View From Within the OAI
Moderators: | Lisa Begg, Ph.D., Director of Research Programs, ORWH Partap Khalsa, D.C., Ph.D, Program Director, NCCAM |
OAI Clinical Centers
10:15 - 10:30 AM | Where is OA Pain Located in the Knee? Methods of Assessment and Patterns C. Kent Kwoh, M.D., PI University of Pittsburgh OAI Clinical Center |
10:30 - 10:45 AM | Effect of Weight Change on Knee Pain in OAI Participants Marc Hochberg, M.D., MPH, PI University of Maryland OAI Clinical Center |
10:45 - 11:00 AM | Knee Pain, Physical Activity and Function in OAI Participants Rebecca Jackson, M.D., PI Ohio State University OAI Clinical Center |
OAI Ancillary Studies
11:00 - 11:15 AM | Thrust and Meniscal Lesions in Knee OA in the OAI Leena Sharma, M.D., Northwestern University, Ancillary Study PI |
11:15 - 11:30 AM | Relation of Knee Alignment and Other Risk Factors to Knee OA David Felson, M.D., MPH, Boston University, Ancillary Study PI |
11:30 - 11:45 AM | The Role of Bone in OA Progression Timothy McAlindon, M.D., MPH, Tufts University, Ancillary Study PI |
Session III — View From Outside the OAI
Moderators: | Bernadette Tyree, Ph.D., Program Director, NIAMS Tamara Harris, M.D., M.S., Senior Investigator, NIA |
11:45 - 12:00 PM | Change in Cartilage Morphometry Over One Year: Studies in the Progression Cohort of the OAI David Hunter, MBBS, Ph.D., MSc, New England Baptist Hospital |
12:00 - 12:15 PM | Strong Association of Bone Marrow Lesions and Effusion with Pain in OA Grace Lo, M.D., Tufts University |
12:15 - 12:30 PM | Instrument Development for the OAI Sharmila Majumdar, Ph.D., University of California San Francisco |
12:30 - 12:45 PM | A Consortium for Analysis of MR Images from the OAI Felix Eckstein, M.D., Paracelsus University, Salzburg, Germany |
12:45 - 1:30 PM Lunch on Concourse Terrace (Lobby Level)
1:30 - 2:00 PM | State of OA Clinical Research — Value of Longitudinal Cohorts Stefan Lohmander, M.D., Ph.D., Lund University, Lund, Sweden |
Session IV — View of the Future
Moderators: | Chhanda Dutta, Ph.D., Branch Chief, NIA Joan McGowan, Ph.D., Musculoskeletal Diseases Division Director, NIAMS |
2:00 - 2:45 PM | Proposal For and Discussion of Extension of Follow Up of OAI Cohort Michael Nevitt, Ph.D., and Charles McCulloch, Ph.D. |
2:45 - 3:20 PM | Q & A Session with OAI Steering Committee — Evaluation Team |
3:20 - 4:00 PM | Q & A Session with OAI Steering Committee & Speakers — Audience |
4:00-4:30 PM | Wrap up and Summary Stephen I. Katz, M.D., Ph.D., Director, NIAMS Richard Hodes, M.D., Director, NIA |