The NIAMS announces that the UCSF Coordinating Center for the OAI has released data from the 60-month follow-up visit of the OAI cohort, including questionnaire data. These data are available to registered users of OAI Online. To date, baseline, 12-month, 24-month, 36-month, 48-month, and 60-month data have been released for the entire cohort; data from the 18-month and 30-month follow-up visit for a subset of participants have been released as well.

Additionally, there are standardized measurements and interpretations of OAI images from selected samples of participants available to registered users on the OAI Online site. The primary focus of these assessments is longitudinal structural outcomes of osteoarthritis. The following datasets have been released:

• Updated Outcomes database that includes endpoint data through the 60-month visit, along with new X-ray outcomes variables
• Updated Imaging Inventory for Study Planning database. This database can be used to facilitate the planning of analyses using the central image assessments and/or OAI images. For your convenience, we have added a new variable that reports the first visit at which rheumatoid arthritis (RA) is diagnosed or an RA medication is used.
• Reliability readings for semi-quantitative measurements and quantitative joint space width from longitudinal sets of knee X-rays
• Revised quantitative cartilage and bone morphology data from longitudinal sets of knee MRIs

Image assessments can be downloaded from the OAI Online website (https://oai.epi-ucsf.org/datarelease/).

Interest in the Osteoarthritis Initiative continues to be high as does the use of the OAI Online website. To date, there are 2,583 people, representing 100 countries, who have registered for OAI Online. A total of 13,683 datasets have been downloaded.