The knee cartilage of a patient with OA thins over time (upper panel: prior to treatment; lower panel: 2 years later, with corticosteroid injections to the knee every 3 months). Repeated corticosteroid injections to the joint may speed cartilage degeneration.

Long-term Benefit of Steroid Injections for Knee Osteoarthritis Challenged

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Tph cells (blue) stimulate antibody production by B cells (green) in joints of people with RA.

Newly Identified T cell Subtype Abundant in Joints of Rheumatoid Arthritis Patients

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Lipocalin 2, a hormone triggered by feeding and produced by osteoblasts, acts on neurons in the hypothalamus to curb appetite and reduce food intake.

Bone-Derived Hormone Curbs Appetite and Weight Gain in Mice

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2017 NIAMS Summer Interns group photo

2017 NIAMS Summer Interns Reflect on Their Experiences

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Photo of woman and child playing with sidewalk chalk.

Genetic Evidence Separates Systemic Juvenile Idiopathic Arthritis from Others in Juvenile Idiopathic Arthritis Family

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The image on the right shows the presence of type VII collagen in skin after gene therapy, compared to untreated skin on the left.

Genetically Modified Skin Grafts Show Promise for Treating Epidermolysis Bullosa

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Photo of a doctor examining a patient's hand.

Immune Reaction at Mucosal Sites Signals Rheumatoid Arthritis Initiation

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Microscope image of bone-forming osteoblasts (light pink) appear on bone (blue) surfaces.

Parathyroid Hormone Signaling Pathway Reveals New Strategy for Treating Osteoporosis

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Butterfly sitting on a hand of a person with psoriasis patches appear on the fingers.

Psoriasis: On the Road to Discovery

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Psoriasis patches (or plaques) on the legs and the scalp characterized by silvery scales.

Questions & Answers About Psoriasis

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A mouse observing a video screen of a scratching demonstrator will begin to scratch itself, too.

Socially contagious itching hardwired into brain

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